Impact of paternal age on intracytoplasmic sperm injection cycle results

Negative influence of paternal age on clinical intracytoplasmic sperm injection cycle outcomes in oligozoospermic patients.

OBJECTIVE To evaluate the effect of male age on clinical outcomes of intracytoplasmic sperm injection (ICSI) cycles, according to sperm concentration. DESIGN Retrospective, observational study. SETTING Assisted reproduction center. PATIENT(S) The study included 1,024 couples undergoing ICSI cycles with fresh spermatozoa. INTERVENTION(S) The influence of paternal age on ICSI outcomes of ...

Effect of Paternal Age on Reproductive Outcomes of Intracytoplasmic Sperm Injection.

The impact of paternal age on reproduction, especially using assisted reproductive technologies, has not been well studied to date. To investigate the effect of paternal age on reproductive outcomes, here we performed a retrospective analysis of 2,627 intracytoplasmic sperm injection (ICSI) cycles performed at the Reproductive Medicine Center of the Third Affiliated Hospital of Guangzhou Medica...

Paternal origin of trisomy 21 following intracytoplasmic sperm injection (ICSI).

One important aspect in the debate on the genetic risks associated with intracytoplasmic sperm injection (ICSI) is the possible increased rate of chromosomal abnormalities in resulting pregnancies. ICSI was performed in a 27 year old man with asthenoteratozoospermia and his 25 year old wife. There was a spontaneous miscarriage at 9 weeks of gestation. Cytogenetic investigation revealed trisomy ...

Denudation and sperm injection interval timing: impact on outcome of intracytoplasmic sperm injection

BACKGROUND Given the importance of timing of denudation and oocyte injection during assisted reproductive technology cycles, a study was undertaken of the impact of timing on the outcome of intracytoplasmic sperm injection in a cohort of patients from a private in vitro fertilization center. METHODS The study included patients who underwent fresh intracytoplasmic sperm injection-embryo transf...

Intracytoplasmic sperm injection (ICSI).